1. Targeted immune modulators for rheumatoid arthritis: effectiveness and value : evidence report Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, April 7, 2017 Subject(s): Arthritis, Rheumatoid -- drug therapyArthritis, Rheumatoid -- immunologyImmunologic Factors -- therapeutic useAbatacept -- therapeutic useAdalimumab -- therapeutic useAntirheumatic Agents -- adverse effectsAntirheumatic Agents -- therapeutic useCertolizumab Pegol -- therapeutic useCost-Benefit AnalysisDrug Therapy, CombinationEtanercept -- therapeutic useImmunologic Factors -- adverse effectsInfliximab -- therapeutic useInterleukin-6 -- antagonists & inhibitorsJanus Kinase Inhibitors -- therapeutic useRandomized Controlled Trials as TopicRituximab -- therapeutic useTumor Necrosis Factors -- antagonists & inhibitorsHumansUnited States