The purpose of this presentation is to assist in teaching the morphological aspects of hematology to medical students, residents and interns, and laboratory technicians. This objective is achieved with the aid of high and low power views of bone marrow aspirates. At the end of each segment, histologic slides are presented, and the viewer is asked to identify the cells seen. The slides are then shown again and discussed. The characteristics of a well prepared blood film are identified first. The program then describes what the viewer should look for and how to select an area for high power examination. Slides are then presented, and cellular detail is described of rubriblasts, prorubricytes, metarubricytes, sideroblasts, and early erythroid precursors. Clinical situations in which these cells would be found are discussed, and the clinical features of several patients are described. In part two of the presentation, histological slides of bone marrow aspirate are presented and discussed in cases of multiple myeloma, chronic lymphocytic leukemia, acute lymphocytic leukemia, acute stem cell leukemia, chronic granulocytic leukemia, an osteoclast found near an actively growing bone tumor, Gaucher's disease, and a tissue mast cell. This video is intended as a simulation of laboratory research with a dual-headed microscope, primarily, a study of blood films. Blood films can be of diagnostic importance, and it is important to correlate them with clinical features. According to one of the presenters, blood film should be thin and rapidly air-dried so that the film can be easily interpreted. Several images of blood films are shown throughout the video and analyzed in great detail, including certain abnormalities in the film that can be indicators for leukemia.
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