1. Enrichment strategies for clinical trials to support determination of effectiveness of human drugs and biological products Publication: Silver Spring, MD : Center for Drug Evaluation and Research, March 2019 Subject(s): Clinical Trials as TopicPrognosisResearch DesignBiomarkers, PharmacologicalBiomarkers, TumorCaptopril -- therapeutic useCardiovascular Diseases -- drug therapyClozapine -- therapeutic useCyclooxygenase 2 Inhibitors -- therapeutic useDrugs, InvestigationalLung Diseases -- drug therapyMedication AdherenceNeoplasms -- drug therapyPatient CompliancePatient SelectionPharmacogeneticsHumansUnited StatesUnited States. Department of Health and Human Services.United States. Food and Drug Administration.