Letter from Francis Crick to Aaron Klug
- Contributor(s):
- The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers Klug, Aaron Crick, Francis, 1916-2004
- Publication:
- Produced: 17 January 1977
- Language(s):
- English
- Format:
- Text
- Subject(s):
- DNA Chromatids
- Genre(s):
- Archival Materials Letters (correspondence)
- Abstract:
- Crick expressed reservations about the evidence used by his two co-authors in support of their idea that chromatids, the one-half of a chromosome that splits off from the other half during cell division, were organized in a hierarchy of helices: the chromatid is a folded and coiled super-solenoid (a long, regular, hollow cylindrical structure), also called the unit fiber, which in turn is formed by a coiled solenoid of smaller diameter, which in turn is formed by coiling the string of nucleosomes, bead-like complexes of DNA and protein.. See Leth Bak, Jesper Zeuthen, and Crick, "Higher-Order Structure of Human Mitotic Chromosomes," Proceedings of the National Academy of Sciences, vol. 74 (April 1977), pp. 1595-99.
- Copyright:
- This item may be under copyright protection; contact the copyright owner for permission before re-use.
- Extent:
- 2 pages
- NLM Unique ID:
- 101584582X242 (See in Profiles in Science)
- Profiles in Science ID:
- SCBBQT
- Permanent Link:
- http://resource.nlm.nih.gov/101584582X242
- Archival Collection:
- The Francis Crick Papers (Profiles in Science)