Klug here reports further results of X-ray diffraction studies of crystals of chromatin in his laboratory. Chromatin is a filamentary (stringy) assembly of DNA and associated basic proteins called histones. It is the form in which genes are organized on the chromosomes.. Nucleosomes, also mentioned in the letter, are distinct complexes of histone and DNA in eukaryotic cells (cells with clearly-defined nuclei), and form specific sections of chromatin. Under the electron microscope nucleosomes appear as bead-like bodies on a string of DNA.
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