Brenner here reported results from his research with mutations of the phages (bacterial viruses) T2 and T4, research designed to match a mutation in the fine structure of a phage gene to changes in a protein whose synthesis the virus triggered when it infected a bacterial cell. Brenner sought to give experimental support to Crick's sequence hypothesis: that the sequence of the bases in DNA specified the order of the amino acids in the polypeptide chain of proteins.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.