This is a lecture by Dr. John K. Frost, Professor of Pathology at Johns Hopkins University School of Medicine, at the 16th Annual Seminar presented by the Houston Society of Clinical Pathologists. After a brief introduction by Dr. S. Donald Greenberg, Dr. Frost presents slides taken from a series of patients suffering from various forms of vaginal cancer. The slides also show diagrams that illustrate how these conditions are diagnosed and how they differ among various cases. One such case is clear cell adenocarcinoma, a cancer of the vaginal wall that occurs in young women whose mothers had taken diethylstilbestrol, a synthetic form of estrogen that was prescribed to women in the mid-20th century to prevent complications in pregnancy.
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