In the early 1950s Fredrickson turned to the study of hereditary abnormalities in plasma (blood) lipoproteins, compounds of proteins and lipids such as fat and cholesterol. In this lecture slide, Fredrickson retrospectively captures the state of knowledge about plasma lipoproteins in 1950. At that time, abnormal plasma lipids were either diagnosed as too much cholesterol, Essential Hypercholesterolemia (EHC), or too much of the fat triglyceride, Essential Hyperlipemia (EHL). Over the next 20 years, Fredrickson and his co-workers achieved a fuller understanding of hereditary abnormalities in the way the body processes lipoproteins (lipid metabolism).
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