Metin and Metactomyosin
- Contributor(s):
- Kaminer, B. Proceedings of the National Academy of Sciences of the United States of America Szent-Gyorgyi, Albert, 1893-1986
- Publication:
- National Academy of Sciences (U.S.), 15 December 1963
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Muscle Contraction Calcium
- Genre(s):
- Archival Materials Articles
- Abstract:
- This study sought to explain the apparent role of calcium ions in muscle contraction, by searching for a component of muscle tissue that would have an affinity for Ca ions. Reasoning that such material would probably have a structure that included negative groups such as sulfites, and knowing that such molecules were often "metachromatic" (i.e., would stain to a different color than that of the dye applied to them), Szent-Gyorgyi tested various muscle components--myosin, actomyosin, and other fractions--for their ability to turn toluidine blue (a lab stain) purple. He extracted a metachromatic protein and called it "metin."
- Copyright:
- This item may be under copyright protection; contact the copyright owner for permission before re-use.
- Extent:
- 4 pages
- NLM Unique ID:
- 101584924X124 (See in Profiles in Science)
- Profiles in Science ID:
- WGBBHZ
- Permanent Link:
- http://resource.nlm.nih.gov/101584924X124
- Archival Collection:
- The Albert Szent-Gyorgyi Papers (Profiles in Science)