Letter from Francis Crick to Sewell Champe
- Contributor(s):
- The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers Crick, Francis, 1916-2004 Champe, Sewell
- Publication:
- Produced: 6 March 1967
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Genetic Code
- Genre(s):
- Archival Materials Letters (correspondence)
- Abstract:
- Crick here responded to Champe's report of results from his research with the rII mutants of the bacterial viruses T2 (phage) which had been used since the early 1950s in genetic mapping experiments. Crick himself discussed results of research with acridine mutants of bacteriophage T2, a different family of mutants in whose study Crick's laboratory specialized and which he used to provide evidence for the three-letter composition of the genetic code. The specific experiments to which Crick referred were with acridine mutants called amber (the triplet UAA) and ochre (UAG) and with the triplet UGA, all three of which signal the end of the polypeptide chain in protein synthesis.
- Copyright:
- This item may be under copyright protection; contact the copyright owner for permission before re-use.
- Extent:
- 2 pages
- NLM Unique ID:
- 101584582X206 (See in Profiles in Science)
- Profiles in Science ID:
- SCBBNZ
- Permanent Link:
- http://resource.nlm.nih.gov/101584582X206
- Archival Collection:
- The Francis Crick Papers (Profiles in Science)