Studies of the Aromatic Circular Dichroism of Staphylococcal Nuclease
- Contributor(s):
- Anfinsen, Christian B. (Christian Boehmer), 1916-1995 Proceedings of the National Academy of Sciences of the United States of America Omenn, Gilbert S. Cuatrecasas, Pedro
- Publication:
- National Academy Press (U.S.), November 1969
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Binding Sites Circular Dichroism Deoxyribonucleases Ribonucleases
- Genre(s):
- Archival Materials Articles
- Abstract:
- In this article, Anfinsen, Omenn, and Cuatrecasas described the circular dichroism spectra of nuclease and of performic acid-oxidized derivative. Their findings suggested that the binding of the nucleotide inhibitor altered the asymmetric environment of certain tyrosyl residues. Furthermore, through titration, a method which can determine a substance or component in a solution by the addition of a liquid reagent of a known strength until a given endpoint, they were subsequently able to determine with greater certainty several of the amino acids present in the amino chain for staphylococcal nuclease.
- Copyright:
- This item may be under copyright protection; contact the copyright owner for permission before re-use.
- Extent:
- 8 pages
- NLM Unique ID:
- 101584571X174 (See in Profiles in Science)
- Profiles in Science ID:
- KKBBLJ
- Permanent Link:
- http://resource.nlm.nih.gov/101584571X174
- Archival Collection:
- The Christian B. Anfinsen Papers (Profiles in Science)